Novel one-pot three component reaction for the synthesis of [2-(alkylsulfanyl)imidazo[1,2-a]pyridin-3-yl](aryl)methanone

Ebrahim Kianmehr; Mohammad Ghanbari; Mehri Nadiri Niri; Reza Faramarzi

doi:10.1021/cc900103r

Novel one-pot three component reaction for the synthesis of [2-(alkylsulfanyl)imidazo[1,2-a]pyridin-3-yl](aryl)methanone

J Comb Chem. 2010 Jan-Feb;12(1):41-4. doi: 10.1021/cc900103r.

Authors

Ebrahim Kianmehr¹, Mohammad Ghanbari, Mehri Nadiri Niri, Reza Faramarzi

Affiliation

¹ School of Chemistry, College of Science, University of Tehran, Tehran, Iran. kianmehr@khayam.ut.ac.ir

PMID: 19904970
DOI: 10.1021/cc900103r

Abstract

A one-pot, three-component reaction between pyridine, phenacyl bromide, and thiocyanate is described. The reaction afforded the corresponding special type of fully substituted imidazo[1,2-a]pyridine derivatives in good yields without using any catalyst or activation.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acetophenones / chemical synthesis*
Bromides / chemistry
Combinatorial Chemistry Techniques*
Molecular Structure
Pyridines / chemical synthesis*
Pyridines / chemistry

Substances

Acetophenones
Bromides
Pyridines
imidazo(1,2-a)pyridine